编辑网络配置文件 nano /etc/netplan/50-cloud-init.yaml

network:
    ethernets:
        ens33:
            addresses:
            - 172.16.110.88/24
            nameservers:
                addresses:
                - 172.16.110.10
                search:
                - ubuntu-server
            routes:
            -   to: default
                via: 172.16.110.253
    version: 2

保存，应用设置 netplan apply